Varicella Disease: Chickenpox & Shingles

Varicella was once a common childhood disease. Due to childhood vaccination initiated in 1996 in the United States, the viral infection has already begun to fade out of common knowledge. Many young adults and adolescents today, have never experienced the itchy blistering rash, or missed days of school because of it. Some people have even begun to contest the necessity of vaccinating against the virus that causes chickenpox infections in children. However, preventing chickenpox can also prevent two painfully debilitating conditions later on in life; Shingles and Postherpetic Neuralgia.

Varicella-Zoster Virus

The Varunknownicella-Zoster Virus (VZV) is a DNA herpesvirus that infects humans and some primates.  It is the cause of both Chickenpox (Varicella disease) and Shingles (Herpes Zoster).

Varicella Disease: Chickenpox

Chickenpox is a highly infectious childhood disease that primarily affects children between the ages of 1 and 9 years old. It causes an itchy vesicular rash to appear on the body, accompanied by fever and malaise.

Chickenpox is self-limiting, and does not require treatment to be resolved. Healthy individuals develop a mild disease that  generally clears within a few weeks. Symptoms such as dehydration, fever, and puritis, can be managed with fluid replacement, acetaminophen, and calamine lotion, respectively. Continue reading

Medicinal Marijuana Alternative Kills French Man.

marijuanamedicalMarijuana was listed as a Schedule 1 drug in 1970. At the time it was considered to have no medicinal purpose; as the discovery of the first cannabinoid receptor wouldn’t occur until the 1980’s. Due to governmental suppression of illicit marijuana use, research into its medicinal use was discontinued.  Recent debates over legalizing marijuana coupled with new understanding of the cannabinoid receptor system in the human body has renewed investigation into the development of pharmaceutical therapeutic alternatives. The alternatives include receptor-based drugs, inhibitors of enzymes that break down endogenous cannabinoids, and synthetic compounds that can modulate how cannabinoids bind to their receptors. Ideally, alternatives should have improved efficacy, potency, duration of action, safety, and the beneficial properties of marijuana, but without the harmful side effects. Continue reading